February 24, 2022

MEDICATIONS LICENSED TO MANAGE MENOPAUSE SYMPTOMS

Systemic HRT

Sequential Regimens

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Method of delivery Name Oestrogen Progestogen
Oral tablets Elleste Duet Estradiol 1mg and 2mg Norethisterone 1mg
Oral tablets Femoston Estradiol 1mg and 2mg Dydrogesterone 10mg
Oral tablets Novofem Estradiol 1mg Norethisterone 1mg
Oral tablets Trisequens Estradiol 2mg / 2mg / 1mg Norethisterone 1mg
Patch Evorel Sequi Estradiol 50mcg Norethisterone 170mcg

Continuous Regimens

Method of delivery Name Oestrogen Progestogen
Oral tablets Bijuve Estradiol 1mg Micronised progesterone 100mg
Oral tablets Angeliq Estradiol 1mg Drospirenone 2mg
Oral tablets Elleste Duet Conti Estradiol 2mg Norethisterone 1mg
Oral tablets Femoston Conti Estradiol 500mcg and 1mg Dydrogesterone 2.5mg and 5mg
Oral tablets Indivina Estradiol 1mg and 2mg Medroxyprogesterone 2.5mg and 5mg
Oral tablets Kliofem Estradiol 2mg Norethisterone 1mg
Oral tablets Kliovance Estradiol 1mg Norethisterone 500mcg
Oral tablets Generic preparation Estradiol 1mg Norethisterone 1mg
Oral tablets Generic preparation Estradiol 2mg Norethisterone 1mg
Oral tablets Generic preparation Conjugated oestrogen 300mcg Medroxyprogesterone 1.5mg
Patch Evorel Conti Estradiol 50mcg Norethisterone 170mcg
Patch Femseven Conti Estradiol 50mcg Levonorgestrel 7mcg
Patch Estradot Conti Estradiol 30mcg and 40mcg Norethisterone 95mcg and 130mcg

Oestrogen Only

Method of delivery Name Oestrogen
Oral tablet Elleste Solo Estradiol 1mg and 2mg
Oral tablet Progynova Estradiol 1mg and 2mg
Oral tablet Zumenon Estradiol 1mg and 2mg
Oral tablet Generic preparation Estradiol 1mg and 2mg
Oral tablet Generic preparation Conjugated oestrogen 300mcg, 625mcg and 1.25mg
Patch Estraderm MX Estradiol 25mcg, 50mcg, 75mcg and 100mcg
Patch Estradot Estradiol 25mcg, 37.5mcg, 50mcg, 75mcg and 100mcg
Patch Evorel Estradiol 25mcg, 50mcg, 75mcg and 100mcg
Patch Femseven Estradiol 50mcg, 75mcg and 100mcg
Gel Sandrena Estradiol 500mcg and 1mg
Gel Oestrogel/dose Estradiol 0.06%
Gel Evorel Estradiol 500mcg per actuation
Spray Lenzetto Estradiol 1.53mg

Progestogens

Method of delivery Name Progestogen
Oral tablets Gepretix Micronised progesterone 100mg
Oral tablets Utrogestan Micronised progesterone 100mg
Oral tablets Generic preparation Progesterone micronised 100mg
Oral tablets Nalvee Dydrogesterone 10mg
Intra-uterine system Mirena Levonorgestrel 20mcg / 24 hours

Management of Genitourinary Syndrome of Menopause

Topical Vaginal Preparations / Tablets

Method of delivery Name Oestrogen / active substance
Vaginal pessary Vagifem Estradiol 10mcg
Vaginal pessary Vagirux Estradiol 10mcg
Vaginal pessary Imvaggis Estriol 30mcg
Vaginal ring Estring (90 day preparation) Estradiol 7.5mcg / 24 hours
Vaginal pessary Generic preparation Estriol 500mcg
Vaginal pessary Gina (over the counter) Estradiol 10mcg
Vaginal pessary Generic preparation Estradiol 10mcg
Vaginal gel Blissel Estriol 50mcg
Vaginal cream Generic preparation Estriol 0.01%
Vaginal cream Generic preparation Estriol 0.1% (1mg/g)
Vaginal cream Ovesse (over the counter) Estriol 0.1% (1mg/g)
Non-oestrogen pessary Intrarosa Prasterone 6.5mg
Oral tablet (SERM) Senshio Ospemifene 60mg

Non-Hormonal Preparations

Method of delivery Name Preparation
Oral tablet for systemic symptoms Livial Tibolone 2.5mg
Oral tablet for systemic symptoms Veoza Fezolinetant 45mg
Oral tablet for genitourinary symptoms Senshio Ospemifene 60mg
Vaginal pessary Intrarosa Prasterone 6.5mg

Reviewed 17 August 2026.
Information sourced from www.mims.co.uk and
BNF (British National Formulary) | NICE.